**Outlook:**Aprea Therapeutics Inc. Common stock is assigned short-term B2 & long-term B2 estimated rating.

**AUC Score :**

**Short-Term Revised**

^{1}:**Dominant Strategy :**Sell

**Time series to forecast n:** for

^{2}

**Methodology :**Statistical Inference (ML)

**Hypothesis Testing :**Ridge Regression

**Surveillance :**Major exchange and OTC

^{1}The accuracy of the model is being monitored on a regular basis.(15-minute period)

^{2}Time series is updated based on short-term trends.

## Summary

Aprea Therapeutics Inc. Common stock prediction model is evaluated with Statistical Inference (ML) and Ridge Regression^{1,2,3,4}and it is concluded that the APRE stock is predictable in the short/long term. Statistical inference is a process of drawing conclusions about a population based on data from a sample of that population. In machine learning (ML), statistical inference is used to make predictions about new data based on data that has already been seen.

**According to price forecasts for 16 Weeks period, the dominant strategy among neural network is: Sell**

## Key Points

- Trust metric by Neural Network
- Can we predict stock market using machine learning?
- Which neural network is best for prediction?

## APRE Target Price Prediction Modeling Methodology

We consider Aprea Therapeutics Inc. Common stock Decision Process with Statistical Inference (ML) where A is the set of discrete actions of APRE stock holders, F is the set of discrete states, P : S × F × S → R is the transition probability distribution, R : S × F → R is the reaction function, and γ ∈ [0, 1] is a move factor for expectation.^{1,2,3,4}

F(Ridge Regression)

^{5,6,7}= $\begin{array}{cccc}{p}_{\mathrm{a}1}& {p}_{\mathrm{a}2}& \dots & {p}_{1n}\\ & \vdots \\ {p}_{j1}& {p}_{j2}& \dots & {p}_{jn}\\ & \vdots \\ {p}_{k1}& {p}_{k2}& \dots & {p}_{kn}\\ & \vdots \\ {p}_{n1}& {p}_{n2}& \dots & {p}_{nn}\end{array}$ X R(Statistical Inference (ML)) X S(n):→ 16 Weeks $R=\left(\begin{array}{ccc}1& 0& 0\\ 0& 1& 0\\ 0& 0& 1\end{array}\right)$

n:Time series to forecast

p:Price signals of APRE stock

j:Nash equilibria (Neural Network)

k:Dominated move

a:Best response for target price

### Statistical Inference (ML)

Statistical inference is a process of drawing conclusions about a population based on data from a sample of that population. In machine learning (ML), statistical inference is used to make predictions about new data based on data that has already been seen.### Ridge Regression

Ridge regression is a type of regression analysis that adds a penalty to the least squares objective function in order to reduce the variance of the estimates. This is done by adding a term to the objective function that is proportional to the sum of the squares of the coefficients. The penalty term is called the "ridge" penalty, and it is controlled by a parameter called the "ridge constant". Ridge regression can be used to address the problem of multicollinearity in linear regression. Multicollinearity occurs when two or more independent variables are highly correlated. This can cause the standard errors of the coefficients to be large, and it can also cause the coefficients to be unstable. Ridge regression can help to reduce the standard errors of the coefficients and to make the coefficients more stable.

For further technical information as per how our model work we invite you to visit the article below:

How do AC Investment Research machine learning (predictive) algorithms actually work?

## APRE Stock Forecast (Buy or Sell)

**Sample Set:**Neural Network

**Stock/Index:**APRE Aprea Therapeutics Inc. Common stock

**Time series to forecast:**16 Weeks

**According to price forecasts, the dominant strategy among neural network is: Sell**

Strategic Interaction Table Legend:

**X axis: *Likelihood%** (The higher the percentage value, the more likely the event will occur.)

**Y axis: *Potential Impact%** (The higher the percentage value, the more likely the price will deviate.)

**Z axis (Grey to Black): *Technical Analysis%**

### Financial Data Adjustments for Statistical Inference (ML) based APRE Stock Prediction Model

- For the purpose of applying paragraphs B4.1.11(b) and B4.1.12(b), irrespective of the event or circumstance that causes the early termination of the contract, a party may pay or receive reasonable compensation for that early termination. For example, a party may pay or receive reasonable compensation when it chooses to terminate the contract early (or otherwise causes the early termination to occur).
- An entity need not undertake an exhaustive search for information but shall consider all reasonable and supportable information that is available without undue cost or effort and that is relevant to the estimate of expected credit losses, including the effect of expected prepayments. The information used shall include factors that are specific to the borrower, general economic conditions and an assessment of both the current as well as the forecast direction of conditions at the reporting date. An entity may use various sources of data, that may be both internal (entity-specific) and external. Possible data sources include internal historical credit loss experience, internal ratings, credit loss experience of other entities and external ratings, reports and statistics. Entities that have no, or insufficient, sources of entityspecific data may use peer group experience for the comparable financial instrument (or groups of financial instruments).
- If, at the date of initial application, determining whether there has been a significant increase in credit risk since initial recognition would require undue cost or effort, an entity shall recognise a loss allowance at an amount equal to lifetime expected credit losses at each reporting date until that financial instrument is derecognised (unless that financial instrument is low credit risk at a reporting date, in which case paragraph 7.2.19(a) applies).
- In some jurisdictions, the government or a regulatory authority sets interest rates. For example, such government regulation of interest rates may be part of a broad macroeconomic policy or it may be introduced to encourage entities to invest in a particular sector of the economy. In some of these cases, the objective of the time value of money element is not to provide consideration for only the passage of time. However, despite paragraphs B4.1.9A–B4.1.9D, a regulated interest rate shall be considered a proxy for the time value of money element for the purpose of applying the condition in paragraphs 4.1.2(b) and 4.1.2A(b) if that regulated interest rate provides consideration that is broadly consistent with the passage of time and does not provide exposure to risks or volatility in the contractual cash flows that are inconsistent with a basic lending arrangement.

*International Financial Reporting Standards (IFRS) adjustment process involves reviewing the company's financial statements and identifying any differences between the company's current accounting practices and the requirements of the IFRS. If there are any such differences, neural network makes adjustments to financial statements to bring them into compliance with the IFRS.

### APRE Aprea Therapeutics Inc. Common stock Financial Analysis*

Rating | Short-Term | Long-Term Senior |
---|---|---|

Outlook* | B2 | B2 |

Income Statement | C | Ba2 |

Balance Sheet | C | C |

Leverage Ratios | Ba3 | Caa2 |

Cash Flow | Baa2 | B1 |

Rates of Return and Profitability | B3 | C |

*Financial analysis is the process of evaluating a company's financial performance and position by neural network. It involves reviewing the company's financial statements, including the balance sheet, income statement, and cash flow statement, as well as other financial reports and documents.

How does neural network examine financial reports and understand financial state of the company?

## Conclusions

Aprea Therapeutics Inc. Common stock is assigned short-term B2 & long-term B2 estimated rating. Aprea Therapeutics Inc. Common stock prediction model is evaluated with Statistical Inference (ML) and Ridge Regression^{1,2,3,4} and it is concluded that the APRE stock is predictable in the short/long term. ** According to price forecasts for 16 Weeks period, the dominant strategy among neural network is: Sell**

### Prediction Confidence Score

## References

- Friedman JH. 2002. Stochastic gradient boosting. Comput. Stat. Data Anal. 38:367–78
- Bottou L. 2012. Stochastic gradient descent tricks. In Neural Networks: Tricks of the Trade, ed. G Montavon, G Orr, K-R Müller, pp. 421–36. Berlin: Springer
- Mnih A, Kavukcuoglu K. 2013. Learning word embeddings efficiently with noise-contrastive estimation. In Advances in Neural Information Processing Systems, Vol. 26, ed. Z Ghahramani, M Welling, C Cortes, ND Lawrence, KQ Weinberger, pp. 2265–73. San Diego, CA: Neural Inf. Process. Syst. Found.
- Bertsimas D, King A, Mazumder R. 2016. Best subset selection via a modern optimization lens. Ann. Stat. 44:813–52
- R. Rockafellar and S. Uryasev. Conditional value-at-risk for general loss distributions. Journal of Banking and Finance, 26(7):1443 – 1471, 2002
- Belloni A, Chernozhukov V, Hansen C. 2014. High-dimensional methods and inference on structural and treatment effects. J. Econ. Perspect. 28:29–50
- Cheung, Y. M.D. Chinn (1997), "Further investigation of the uncertain unit root in GNP," Journal of Business and Economic Statistics, 15, 68–73.

## Frequently Asked Questions

Q: What is the prediction methodology for APRE stock?A: APRE stock prediction methodology: We evaluate the prediction models Statistical Inference (ML) and Ridge Regression

Q: Is APRE stock a buy or sell?

A: The dominant strategy among neural network is to Sell APRE Stock.

Q: Is Aprea Therapeutics Inc. Common stock stock a good investment?

A: The consensus rating for Aprea Therapeutics Inc. Common stock is Sell and is assigned short-term B2 & long-term B2 estimated rating.

Q: What is the consensus rating of APRE stock?

A: The consensus rating for APRE is Sell.

Q: What is the prediction period for APRE stock?

A: The prediction period for APRE is 16 Weeks

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